Sensory evaluation of dairy supplements enriched with reduced iron, ferrous sulfate or ferrous fumarate.

Tolerability of different oral iron supplements: a systematic review.

OBJECTIVE A systematic review was conducted to analyze the tolerability of several oral iron supplements based on data obtained in available publications and to report the incidence of adverse effects (AEs) for each supplement both overall and gastrointestinal. METHODS Electronic databases - Medline, the Cochrane Library, and Embase were searched for studies published up to January 2009. Clin...

Comparison of a combination ferrous fumarate product and a polysaccharide iron complex as oral treatments of iron deficiency anemia: a Taiwanese study.

Despite efforts to improve iron supplements for iron deficiency anemia, there is no consensus on products that balance efficacy, safety and tolerability, and cost. Ferrous products are effective, but they are associated with more gastrointestinal side effects than ferric products. Ferric products tend to have lower absorption. We present results from a 12-week study that randomized 72 people wi...

Pharmacokinetics of Dolutegravir When Administered With Mineral Supplements in Healthy Adult Subjects

All commercially available integrase inhibitors are 2-metal binders and may be affected by co-administration with metal cations. The purpose of this study was to evaluate the effect of calcium and iron supplements on dolutegravir pharmacokinetics and strategies (dose separation and food) to attenuate the effects if significant reductions in dolutegravir exposure were observed. This was an open-...

Feed Additive Name(s): Ferrous chelate of glycine hydrate Ferrous/iron chelate of amino acids hydrate Ferrous fumarate Ferric oxide Ferric chloride hexahydrate Ferrous sulfate monohydrate

Absorption of therapeutic preparations of iron measured with a whole body counter.

The Oxford Whole Body Counter was used to measure absorption from various therapeutic preparations of iron in five groups of subjects. Succinic acid enhanced absorption of iron when added to a solution of ferrous fumarate, but not when given with tablets of ferrous fumarate or ferrous sulphate. Ferrous fumarate plus ascorbic acid was absorbed better than ferrous fumarate alone but no better tha...